Collins, 74, was brought to Biloxi Regional Medical Center where he died shortly before 1 a.m., Harrison County Deputy Coroner Brian Switzer said.
Switzer said Collins died of natural causes.
Collins is known from his TV show-host work with HOUR MAGAZINE and as host of the Miss America pageant, both in the 1980s.
His soap roles included Bob Kerry in DIRTY SEXY MONEY and Harry Curtis in THE YOUNG AND THE RESTLESS.
He starred in the TV series THE SIXTH SENSE in the 1970s and THE WACKIEST SHIP IN THE ARMY in the '60s. He guest-starred in movies including Airport and Angel in My Pocket.
In 1992 he played Zack Taylor in the TV movie, Secrets, starring with Christopher Plummer, Linda Purl and Stephanie Beacham.
Collins' next of kin is listed as Mary Ann Mobley, a former Miss America, who appeared in FALCON CREST and GENERAL HOSPITAL. They were married in 1967 and had one daughter, Clancy Collins White.
Watch Collins interview legendary Jane Wyman about FALCON CREST in 1986 in the HOUR MAGAZINE clip below:
Here's a 1987 clip with GENERAL HOSPITAL stars Finola Hughes and Ian Buchanan appearing in the show:
Jackie Zeman was a guest in 1986:
Chris Robinson and Josh Taylor were also on in 1986:
DAYS OF OUR LIVES star Kristian Alfonso appear as well:
ONE LIFE TO LIVE's Erika Slezak once gave a tour of her home: