In the premiere, "Pilot," Savannah ("Savi") is a successful career woman working toward the next phase in her life -- both professionally and personally -- bucking for partner at the law firm where she works while also trying to start a family with her husband, Harry. But when their fertility issues begin to take center stage, Savi finds herself attracted to her flirtatious colleague, Dominic. Savi's free-spirited and capricious baby sister, Josslyn, couldn't be more different, living single, serial dating and partying. A real estate agent, Josslyn has no interest in a committed, long-term relationship.
Their common best friend, April, is a recent widow and mother of a ten-year-old daughter. After she receives her late husband's lucrative life insurance check, she begins getting prank phone calls and tells her closest girlfriends that she's convinced her husband is still alive. Another long-time friend, Karen, is a therapist with her own thriving practice, reconnecting with the girls after her involvement in a complicated relationship with a wealthy, married patient goes too far: She was having an affair with a terminally ill client to whom she had prescribed morphine.
These four friends find support and guidance with each other as they brave their turbulent journeys and life's storms of excitement, secrecy and betrayal, all the while bound by the complex relationships they've created.
MISTRESSES stars Alyssa Milano as Savannah ("Savi") Davis, Yunjin Kim as Karen Kim, Rochelle Aytes as April Malloy, Jes Macallan as Josslyn Carver, Brett Tucker as Harry Davis, Jason George as Dominic Taylor and Erik Stocklin as Sam Grey.
"Pilot" guest stars Penelope Ann Miller as Elizabeth Grey, John Schneider as Thomas Grey, Shannyn Sossamon as Alex, Cameron Bender as Richard, Kate Beahan as Miranda and Sunkrish Bala as Hamid.
"Pilot" teleplay was written by K.J. Steinberg. Cherie Nowlan directed.
The series is executive-produced by Rina Mimoun (PRIVILEGED, GILMORE GIRLS), K.J. Steinberg (GOSSIP GIRL), Robert Sertner (REVENGE) and Douglas Rae. The series is from ABC Studios.