In the season finale, titled "Perfect Storm", Grey Sloan Memorial Hospital enters crisis mode as the storm rages, resources become scarce and patients flood in by the busload.
Meanwhile, one of the doctors fights for their life.
Watch a sneak peek below:
GREY'S ANATOMY stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, Kevin McKidd as Owen Hunt, Jessica Capshaw as Arizona Robbins, Jesse Williams as Jackson Avery and Sarah Drew as April Kepner.
"Perfect Storm" was written by Stacy McKee and directed by Rob Corn.